Wonderful! And very helpful. Do you suggest us all submitting our versions of this, although we are not therapists or providers, but parents of ROGD kids?
They give a research evidence summary in narrative form.
However, note that the research for under 18's was just rigorously evaluated using modified GRADE by the UK NICE reports, which found (check the critical outcomes for both):
"The critical outcomes for decision making are impact on gender dysphoria, impact on mental health and quality of life. The quality of evidence for all these outcomes was assessed as very low certainty using modified GRADE. "
Also Hembree et al 2017 the endocrine society guidelines evaluated the evidence for treatment as well (low quality)
Yet in this document it says instead: " this emerging evidence base indicates general improvement in the lives of transgender adolescents who, following careful assessment, receive requested gender affirming medical treatment. Further, rates of reported regret during the study monitoring periods are low. Taken as a whole, the data show that early medical intervention—as part of broader combined assessment and treatment approaches focused on gender dysphoria and general well-being— can be effective and helpful for many transgender adolescents seeking these interventions. "
which has not been shown!
similarly later they say that not giving puberty blockers is not a neutral act, with a study saying people were harmed by not getting them, but again, giving puberty blockers has not been shown to help, that was the point of one of the NICE evidence reviews.
One long term outcome from Dutch protocol is here: Puberty suppression in a gender-dysphoric adolescent: a 22-year follow-up (Cohen-Kettenis et al, 2011), only 1 person.
agree about 2 years, de Vries 2014 being too short--
regret studies show regret/detransition on average 4-5-10 years later (so 2 years after surgery is...too soon to say), 4 ish years (low end)
Detransition-Related Needs and Support: A Cross-Sectional Online Survey (Vandenbussche, 2021)
slightly > 4 years, Littman, 2021, Individuals Treated for Gender Dysphoria with Medical and/or Surgical Transition Who Subsequently Detransitioned: A Survey of 100 Detransitioners (Littman, 2021)
130 months (note you can't use their regret rate reliably, they lost 36% of people): The Amsterdam Cohort of Gender Dysphoria Study (1972-2015): Trends in Prevalence, Treatment, and Regrets (Wiepjes et al, 2018)
Wonderful! And very helpful. Do you suggest us all submitting our versions of this, although we are not therapists or providers, but parents of ROGD kids?
Yes, anyone who has something to say about this should take the opportunity.
You are so fast!!!!! Thank you!
for methodology, they have ignored the rigorous research reviews which just came out. Instead...
They give a research evidence summary in narrative form.
However, note that the research for under 18's was just rigorously evaluated using modified GRADE by the UK NICE reports, which found (check the critical outcomes for both):
"The critical outcomes for decision making are impact on gender dysphoria, impact on mental health and quality of life. The quality of evidence for all these outcomes was assessed as very low certainty using modified GRADE. "
hormones: https://arms.nice.org.uk/resources/hub/1070871/attachment
puberty blockers: https://arms.nice.org.uk/resources/hub/1070905/attachment
Also Hembree et al 2017 the endocrine society guidelines evaluated the evidence for treatment as well (low quality)
Yet in this document it says instead: " this emerging evidence base indicates general improvement in the lives of transgender adolescents who, following careful assessment, receive requested gender affirming medical treatment. Further, rates of reported regret during the study monitoring periods are low. Taken as a whole, the data show that early medical intervention—as part of broader combined assessment and treatment approaches focused on gender dysphoria and general well-being— can be effective and helpful for many transgender adolescents seeking these interventions. "
which has not been shown!
similarly later they say that not giving puberty blockers is not a neutral act, with a study saying people were harmed by not getting them, but again, giving puberty blockers has not been shown to help, that was the point of one of the NICE evidence reviews.
And no one knows the regret rates. They don't follow up long enough or studies lose people, for adolescents, here is a discussion: https://segm.org/unknown_gender_transition_regret_rate_adolescents
One long term outcome from Dutch protocol is here: Puberty suppression in a gender-dysphoric adolescent: a 22-year follow-up (Cohen-Kettenis et al, 2011), only 1 person.
Is not happy with sexual part of body :(.
agree about 2 years, de Vries 2014 being too short--
regret studies show regret/detransition on average 4-5-10 years later (so 2 years after surgery is...too soon to say), 4 ish years (low end)
Detransition-Related Needs and Support: A Cross-Sectional Online Survey (Vandenbussche, 2021)
slightly > 4 years, Littman, 2021, Individuals Treated for Gender Dysphoria with Medical and/or Surgical Transition Who Subsequently Detransitioned: A Survey of 100 Detransitioners (Littman, 2021)
130 months (note you can't use their regret rate reliably, they lost 36% of people): The Amsterdam Cohort of Gender Dysphoria Study (1972-2015): Trends in Prevalence, Treatment, and Regrets (Wiepjes et al, 2018)
8-9 years (Dhejne et al, 2014)
for those considering MTF, puberty blockers block male sexual desire, which might be relevant for their bodies getting in touch with their minds....https://www.jsm.jsexmed.org/article/S1743-6095(17)31635-1/fulltext